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Content:
EMBASE provides current and comprehensive information on drugs and
pharmacology, and all other aspects of human medicine and related
disciplines.
EMBASE, is a current and comprehensive pharmacological and
biomedical database. As of January 2008, it contained over 12
million documents from 1974 to date - with approximately 600,000
records being added annually.
In the summer of 2007, EMBASE Classic was loaded on DataStar. This
archive takes EMBASE coverage back to 1947 and includes an
additional 1.8 million documents. This archive is in the same format
as the rest of the database, some 90% of documents have abstracts,
and current EMTREE indexing is applied throughout. Note however that
some paragraphs are not populated in the archive - refer to the
Notes section of this Guide. From July 2009, EMBASE Classic ceased
being a subscriber-only file; it is now available to all users.
EMBASE Classic is available in two databases: EM73 (1947-1973), and
EMXX (1947 to date).
EMBASE features unique international journal coverage and Includes
many important journals from Europe and Asia not found in other
biomedical databases; overall coverage of approximately 5,000
journals published in 70 countries.
EMBASE covers the whole world's biomedical literature whilst
concentrating in particular on European sources. The emphasis of the
database is on the pharmacological effects of drugs and chemicals.
Additional areas of coverage are human medicine and biological
sciences relevant to human medicine, health affairs (occupational
and environmental health, health economics, policy and management),
drug and alcohol dependence, psychiatry, forensic science, pollution
control, biotechnology, medical devices and alternative medicine.
The database provides the full author abstract for 80% of recent
articles. EMBASE is extremely current: articles are indexed and
appear online on average within 10-15 days of receipt of the
original journal.
An interactive thesaurus for the EMTREE classification system is
available in each of the EMBASE files.
Use EMBASE to answer specific questions like:
- What treatments are proposed for NSAID-induced
Gastrointestinal lesions with cytotec?
- Are there any reports of educating children about the
dangers of smoking?
- What has been published on the sensitivity to naltrexone in
rats?
Sources:
EMBASE has unique international journal coverage; overall,
approximately 5,000 journals published in 70 countries are included.
AN - Accession number & update
2006187040 20071005.
TI - Title
Percutaneous transluminal angioplasty for hepatic arterial
occlusion following hepatic arterial infusion chemotherapy.
SO - Source
Australasian Radiology, {Australas-Radiol}, February 2006, vol.
50, no. 1, p. 82-86, 17 refs, CODEN: AURDA, eISSN: 1440-1673,
ISSN: 0004-8461.
AU - Author(s)
Yamagami-T, Iida-S, Kato-T, Takegi-H, Nishimura-T.
IN - Author affiliation
Dr.T.Yamagami: Department of Radiology, Graduate School of
Medical Science, Kyoto Prefectural University of Medicine, 465
Kajii, Kawaramachi-Hirokoji, Kamigyo, Kyoto 602-8566, Japan.
Email: yamagami@koto.kpu-m.ac.jp.
AB - Abstract
We report a case in which hepatic arterial occlusion developed
during repeated hepatic arterial infusion chemotherapy through an
implanted port-catheter system for advanced malignant hepatic
neoplasia. After successful recanalization of the hepatic artery
by using percutaneous transluminal angioplasty, another port-
catheter system was placed percutaneously by interventional
radiology techniques, allowing the continuation of hepatic
arterial infusion chemotherapy. 2006 Royal Australian and New
Zealand College of Radiologists.
DE - Descriptors
Major medical terms:
ARTERY-OCCLUSION*/ CO (complication), DI (diagnosis), DT
(drug therapy), TH (therapy);
CANCER-CHEMOTHERAPY*;
LIVER-ARTERY-OCCLUSION*+/ CO (complication), DI
(diagnosis), DT (drug therapy), TH (therapy);
PERCUTANEOUS-TRANSLUMINAL-ANGIOPLASTY*
Minor medical terms:
ADULT;
ANTICOAGULANT-THERAPY;
ARTERIOGRAPHY;
ARTERY-CATHETERIZATION;
ARTICLE;
BLOOD-CLOT-LYSIS;
CASE-REPORT;
CELIAC-ARTERY;
COLON-CANCER/SU (surgery);
DRUG-INFUSION;
GUIDE-WIRE;
HEPATIC-ARTERY;
HUMAN;
INTERVENTIONAL-RADIOLOGY;
LIVER-METASTASIS/CO (complication);
MALE;
OUTPATIENT-CARE
Minor drug terms:
ANTINEOPLASTIC-AGENT/DT (drug therapy), IA (intraarterial
drug administration);
CONTRAST-MEDIUM;
ENBUCRILATE;
HEPARIN/DT (drug therapy), IV (intravenous drug
administration);
IODINATED-POPPYSEED-OIL;
PLASMINOGEN-ACTIVATOR;
UROKINASE/DT (drug therapy), IA (intraarterial drug
administration).
RN - CAS Registry numbers
25154-80-7 6606-65-1 (enbucrilate); 37187-54-5 8057-48-5
8065-01-8 9005-48-5 (heparin); 8001-40-9 8002-46-8 8006-56-2
8006-57-3 (iodinated poppyseed oil); 9039-53-6 (plasminogen
activator); 139639-24-0 (urokinase).
MF - Manufacturer
Aventis (Japan); Mochida (Japan).
TN - Tradenames
heparin (Aventis, Japan); uronase (Mochida, Japan).
DM - Device manufacturer
Boston-Scientific (USA); Braun (Germany); Clinical-Supply
(Japan); Cordis (USA); Guerbet (France); Terumo (Japan); Toray
(Japan).
DN - Device tradenames
P-U Celsite Port (Toray, Japan); Renegade (Boston Scientific,
USA); Savvy (Cordis, USA).
SH - Subject headings
Radiology;
Cancer;
Biophysics-Bioengineering-and-Medical-Instrumentation;
Drug-Literature-Index;
Gastroenterology.
LG - Language
English.
LS Language of summary
English.
PT - Publication type
Journal, Article.
CP - Country of publisher
Australia.
DO - Digital object identifier
<http://dx.doi.org/10.1111/j.1440-1673.2005.01534.x>.
YR - Publication year
2006.
DT - Publication date
20060200.
ED - Entry date
Date created: 20060509.
AN - Accession number & update
2006047188 20071005.
TI - Title
Has the kouprey (Bos sauveli Urbain, 1937) been domesticated in
Cambodia?
TT - Title in original lang.
Le kouprey (Bos sauveli Urbain, 1937) a-t-il été domestiqué au
Cambodge?
SO - Source
Comptes Rendus - Biologies, {C-R-Biol}, February 2006, vol. 329,
no. 2, p. 124-135, 42 refs, CODEN: CRBOC, ISSN: 1631- 0691.
AU - Author(s)
Hassanin-Alexandre, Ropiquet-Anne, Cornette-Raphael,
Pfeffer-Pierre, Tranier-Michel, Candegabe-Philippe,
Lemaire-Michèle.
IN - Author affiliation
A.Hassanin: UMR 5202, Département Systématique et Evolution,
Museum National d'Histoire Naturelle, 55 Rue Buffon, 75005 Paris,
France.
Email: hassanin@mnhn.fr.
AB - Abstract
The kouprey (Bos sauveli Urbain, 1937) is a very rare bovid
species of Cambodia, which may be extinct in the wild, as no
living specimen has been observed for a long time. Here, we
describe a complete taxidermy mount, which presents astonishing
morphological similarities with the kouprey. The animal was
mounted in 1871 at the National Museum of Natural History in
Paris, where it was referenced as No. 1871-576. It was deposited
at the Natural History Museum of Bourges, France, in 1931, where
it is still conserved today. To clarify the taxonomic status of
the specimen of Bourges, DNA was extracted from a piece of bone
taken on the mandible, and two different fragments of the
mitochondrial cytochrome gene were independently amplified and
sequenced.
DE - Descriptors
Major medical terms:
TAXONOMIC-RANK*
Minor medical terms:
ARTICLE;
CAMBODIA;
CATTLE;
DNA-EXTRACTION;
DOMESTICATION;
GENDER-IDENTITY;
GENE-AMPLIFICATION;
GENE-SEQUENCE;
GENETIC-TRAIT;
HYBRIDIZATION;
MALE;
MORPHOLOGY;
NONHUMAN;
NUCLEOTIDE-SEQUENCE;
PHENOTYPE;
PHYLOGENY;
POLYMERASE-CHAIN-REACTION;
SEQUENCE-ANALYSIS;
WILD-TYPE
Minor drug terms:
CYTOCHROME-B/EC (endogenous compound);
DNA/EC (endogenous compound);
DNA-FRAGMENT/EC (endogenous compound).
RN - CAS Registry numbers
9035-37-4 (cytochrome b); 9007-49-2 (DNA).
DS - Gene data
GENBANK-AA222679-B;
GENBANK-AB077313-B;
GENBANK-AB077314-B;
GENBANK-D34636-B;
GENBANK-D82889-B;
GENBANK-D82891-B;
GENBANK-D82895-B;
GENBANK-D88634-B;
GENBANK-DQ275470-B;
...
SH - Subject headings
Developmental-Biology-and-Teratology;
Clinical-and-Experimental-Biochemistry.
LG - Language
French; English.
LS - Language of summary
English; French.
PT - Publication type
Journal, Article.
CP - Country of publisher
France.
AV - Availability
Publisher item identifier: S1631069105002258.
DO - Digital object identifier
<http://dx.doi.org/10.1016/j.crvi.2005.11.003>.
YR - Publication year
2006.
DT - Publication date
20060200.
ED - Entry date
Date created: 20060213.
AN - Accession number & update
19833653 MEDLINE 20100112.
TI - Title
Effects of environmental change on wildlife health.
SO - Source
Philosophical Transactions of the Royal Society B: Biological
Sciences, {Philos-Trans-R-Soc-B-Biol-Sci}, 27 November 2009, vol.
364, no. 1534, p. 3429-3438, 112 refs, CODEN: PTRBA, eISSN:
1471-2970, ISSN: 0962-8436.
Publisher: Royal Society of London, 6 Carlton House Terrace,
London, SW1Y 5AG, UK.
AU - Author(s)
Acevedo-Whitehouse-Karina, Duffus-Amanda-L-J.
IN - Author affiliation
K. Acevedo-Whitehouse: Institute of Zoology, Zoological Society
of London, Regent's Park, London NW1 4RY, UK.
Email: karina.acevedo-whitehouse@ioz.ac.uk.
AB - Abstract
Environmental change has negatively affected most biological
systems on our planet and is becoming of increasing concern for
the well-being and survival of many species. At an organism
level, effects encompass not only endocrine disruptions,
sex-ratio changes and decreased reproductive parameters, but also
include teratogenic and genotoxic effects, immunosuppression and
other immune-system impairments that can lead directly to disease
or increase the risk of acquiring disease. Living organisms will
strive to maintain health by recognizing and resolving abnormal
situations, such as the presence of invading microorganisms or
harmful peptides, abnormal cell replication and deleterious
mutations. However, fast-paced environmental changes may pose
additional pressure on immunocompetence and health maintenance,
which may seriously impact population viability and persistence.
Here, we outline the importance of a functional immune system for
survival and examine the effects that exposure to a rapidly
changing environment might exert on immunocompetence. We then
address the various levels at which anthropogenic environmental
change might affect wildlife health and identify potential
deficits in reproductive parameters that might arise owing to new
immune challenges in the context of a rapidly changing
environment. Throughout the paper, a series of examples and case
studies are used to illustrate the impact of environmental change
on wildlife health. © 2009 The Royal Society.
DE - Descriptors
Major medical terms:
CLIMATE-CHANGE*;
WILD-ANIMAL*.
Minor medical terms:
ANIMAL;
IMMUNOLOGY;
REPRODUCTION;
REVIEW;
TIME.
LG - Language
English.
LS - Language of summary
English.
PT - Publication type
Journal, Review.
CP - Country of publisher
UK.
AV - Availability
URL: <http://rstb.royalsocietypublishing.org/content/364
/1534/3429.full.pdf>.
DO - Digital object identifier
<http://dx.doi.org/10.1098/rstb.2009.0128>.
YR - Publication year
2009.
DT - Publication date
20091127.
ED - Entry date
Date created: 20100111.
Label/description Example
AN Accession number 1_: 2006310491.AN.
& update - see Limit Options
- Replacement documents only 2_: RT=R
- unique-MEDLINE documents
only (new Jan 2010; see
also Notes, below) 3_: MEDLINE=YES
TI Title 4_: GHRELIN ADJ MRNA WITH
ADEMOAS.TI.
TT Title in original language 5_: FUMAR WITH ADOLESCENTES.TT.
CF Conference information 6_: IDIOTYPE ADJ NETWORKS.CF.
- see also Notes below -
SO Source 7_: NEUROENDOCRINOLOGY ADJ
LETTERS.SO.
or 8_: NEUROENDOCRINOLOGY.SO.
or 9_: J-PEDIATR.SO
or 10_: ..ROOT PEDIATR.SO.
..ROOT SO= for a list of
Journals in EMBASE
- publication date - see DT/YR below
- volume number 11_: VOLUME=27
- issue number 12_: ISSUE=5
- start page 13_: PAGE=169
- number of references 14_: 22 ADJ REFS.SO.
- CODEN 15_: NLETD.SO.
- ISSN/eISSN 16_: 0172-780X
- ISBN 17_: 9780444813435.SO.
- priority journals 18_: PRIORITY=YES
AU Author(s) 19_: WASKO-RYSZARD.AU.
or 20_: GUERRA WITH ARMANDO.AU.
or 21_: BEDNAREK-J$.AU.
or 22_: EDITOR WITH
OSTERHAUS.AU.
- for a list of authors
with the same surname 23_: ..ROOT RIVERA.AU.
IN Author affiliation 24_: POZNAN.IN.
AB Abstract 25_: RABIES ADJ VACCINE.AB.
- documents with abstracts 26_: ABSTRACT=YES
DE EMTREE terms - see Notes below, and BASE
guide for most effective
searching using the
EMTREE thesaurus -
27_: BRONCHUS-REACTIVITY
or 28_: BRONCHUS ADJ
REACTIVITY.DE.
- term with subheading 29_: ASTHMA WITH DT.
- exploded term 30_: ASTHMA#
- relating to humans 31_: HUMAN=YES
- animals 32_: ANIMAL=YES
- males 33_: MALE=YES
- females 34_: FEMALE=YES
- adults 35_: ADULT=YES
- children 36_: CHILD=YES
- review articles 37_: REVIEW=YES
- see also Notes below -
MJ Major EMTREE terms - as per DE -
MN Minor EMTREE terms - as per DE -
RN CAS registry numbers 38_: 125978-95-2
or 39_: NITRIC-OXIDE-
SYNTHASE.RN.
DS Gene data 40_: X16147.DS.
- submitted to a molecular
sequence databank 41_: DS=A
- sequence numbers referred
to only 42_: DS=B
MF Manufacturer 43_: ASTRA.MF.
- documents with
manufacturers' names
(drug or device) 44_: MANUFACTURER=YES
TN Tradename 45_: XYLOCAINE.TN.
- documents with tradenames
(drug or device) 46_: TRADENAME=YES
DM Device manufacturer 47_: BUCKINGHAM.DM.
DN Device tradename 48_: VITALOGRAPH.DN.
SH Section headings 49_: CHEST ADJ DISEASES.SH.
..ROOT SH= for a list
LG Language 50_: LG=ENGLISH
..ROOT LG= for a list
LS Language of summary 51_: LS=FRENCH
..ROOT LS= for a list
PT Publication/article type 52_: PT=JOURNAL
..ROOT PT= for a list
CP Country of publisher 53_: UK.CP.
AV Availability 54_: PUBLISHER.AV.
DO Digital object identifier - not searchable -
YR Publication year 55_: YEAR=1998
- see also Limit Options -
DT Publication date 56_: DATE=20070726
57_: MONTH=200707
- see also Limit Options -
- see also Notes below -
ED Entry date 58_: 20070726.ED.
- see also Limit Options -
1_: LIGNOCAINE SAME ASTHMA.TI.
DATE Publication date 2_: ..L 1 DATE=20071012
MONTH Publication month 3_: ..L 1 MONTH GT 200612
YEAR Publication year 2_: ..L 1 YEAR>1997
ED Entry date 3_: ..L 1 ED LT 19970726
UDATE Update date 3_: ..L 1 UDATE GT 20071231
UMONTH Update month 4_: ..L 1 UMONTH WL 200605,
200606
By paragraph - title _: ..P TI 1,3,5-10
SHORT AN TI TT SO AU IN YR
MEDIUM AN TI TT SO AU IN AB LG YR
LONG AN TI TT SO AU IN AB DE (MJ MN) RN DS MF TN DM DN SH LG PT
YR
ALL AN TI TT CF SO AU IN AB DE (MJ MN) RN DS MF TN DM DN SH LG
LS PT CP AV DO YR DT ED
FREE AN TI TT DE (MJ MN) RN LG LS PT YR DT ED
_: ..P MEDIUM 1-5.
Running Alerts in EMBASE:
Elsevier supplies three types of update documents:
- New (delivered daily)
- Replacements (delivered erratically, though theoretically these
could be delivered on a daily basis)
- Deletions (again, erratically though they too could be delivered
daily)
Alerts are only run on new documents.
Alerts are run the day after the update is received by us.
Replacements can be identified in EMBASE by the letter 'R' in the
accession number paragraph. It is possible to find these by adding
the search 'RT=R' to your strategy.
AN - Accession number: Unique-MEDLINE documents
Embase® has been enhanced by the producer, Elsevier, with indexed
MEDLINE® records drawn from journals which have not previously been
available in Embase. The new records began appearing in January, and
an archive of more than seven million records will be loaded later
in 2010.
This change increases the number of journals covered in Embase from
approximately 5,000 to approximately 7,000. In Embase you can use
Emtree terms to search across all records. Please note that only
'completed' documents from MEDLINE are currently appearing in
Embase. Embase is not including documents with a different status,
including records that are described as 'In-process',
'In-data-review', 'Publisher', and 'Pubmed-not-MEDLINE'.
These documents can be identified by the presence of a 'MEDLINE'
flag in the Accession number paragraph. They can be explicitly
included in or excluded from a search with the MEDLINE=YES
quick-code, e.g.
_: MEDLINE=YES
These records will be included in alerts running in Embase. FAQs
will be available very soon, including advice for those wishing to
exclude MEDLINE-originated records from Embase alerts.
CF - Conference information
This paragraph is only populated in a small number of documents -
originally loaded between 1990 and 1992.
DE - Descriptors:
The DE paragraph contains descriptors from the EMTREE Thesaurus,
which consists of almost 56,000 controlled drug and medical terms.
EMTREE is available online as an interactive thesaurus (use the
commands..THES, ..TREE/..EXPL) and in the database EVOC.
HUMAN=YES and ANIMAL=YES - changes implemented in 2009:
These two quick-codes have been considerably simplified for the 2009
reload. This has three benefits:
1. To make it more transparent to the user why a record has been
retrieved.
2. To improve relevance of retrieval.
3. To enable us to load updates onto DataStar more quickly.
These changes were made in consultation with EMTREE specialists at
Elsevier.
HUMAN=YES
Searching HUMAN=YES now retrieves all records indexed with one or
more of the following EMTREE terms:
- the specific term 'HUMAN'
- terms containing the word 'CASE' (e.g. CASE-STUDY)
- terms containing the word 'CLINICAL' (e.g. CONTROLLED-CLINICAL-
TRIAL)
- terms containing the word 'CHILD' (e.g. PRESCHOOL-CHILD)
This contrasts with the pre-2009 situation where some 3800 specific
EMTREE terms (including 'BASEBALL and 'MARKUP-LANGUAGE') were used
to create HUMAN=YES.
To replicate the pre-2009 retrieval associated with HUMAN=YES, the
following search is a good equivalent:
HUMAN# OR NAMED-GROUPS-OF-PERSONS# OR HEALTH-CARE-CONCEPTS# OR
SOCIETY# OR CLINICAL-STUDY# OR CHILD#
Or refer to appendix 3 of the BASE database guide for a full list of
all the EMTREE terms used before the 2009 reload to generate
HUMAN=YES.
ANIMAL=YES:
Searching ANIMAL=YES now retrieves all records indexed with one or
more of the following EMTREE terms:
- terms containing the word 'ANIMAL'
- terms containing the word 'RAT'
- terms containing the word 'MOUSE'
- terms containing the word 'RABBIT'
- terms containing the word 'DOG'
- terms containing the word 'PIG'
- terms containing the word 'SWINE'
- terms containing the word 'CATTLE'
- terms containing the word 'CHICKEN'
- terms containing the word 'MONKEY'
- terms containing the word 'CAT'
The last ten terms represent the most frequently posted terms in the
EXPERIMENTAL-ANIMAL hierarchy of EMTREE.
This contrasts with the pre-2009 situation where some 900 terms were
used to create ANIMAL=YES (including 'COMB' and 'SMEGMAMORPHA')
To replicate the pre-2009 retrieval associated with ANIMAL=YES, the
following search is a good equivalent:
INVERTEBRATE# OR (VERTEBRATE# NOT HUMAN#) OR ANIMAL-ANATOMY# OR
NONHUMAN#
Or refer to appendix 4 of the BASE database guide for a full list of
all the EMTREE terms used before the 2009 reload to generate
ANIMAL=YES.
DT - Publication date
Not all documents have a specific publication date, but this
paragraph is populated for all documents in the format YYYYMMDD. For
those documents taken from weekly, bi-weekly, monthly, quarterly,
annual, etc. publications, the month and date figures may be
zero-filled. For example a 'July 2007' publication date will show as
'20070700', a '2007' publication date will show as '20070000'.
EMBASE (EMED) and EMBASE Alert (EMBA)
Elsevier supplies a sister-file to EMBASE called EMBASE Alert. This
contains the latest eight weeks of information, without any indexing
- in order to have the information available as quickly as possible.
Every item which appears in EMBASE Alert (EMBA) will later appear in
EMBASE (EMED). Usually the delay between appearance in EMBA and then
in EMED is just a matter of a few days, often less than a week.
EM73 - paragraphs not populated
A number of paragraphs in the current EMBASE files are not populated
in the pre-1974 EMBASE Classic archive file. These are:
- CT (Conference title)
- CP (Country of publisher)
- MF (Manufacturer)
- TN (Tradename)
- DT (Publication date)
..RANK and ..MAP: available in AU, SO, MJ and YR paragraphs.
You may find some discrepancy between the number of documents that
is listed in the RANK table and the number of documents retrieved if
that terms is selected for searching. This is because the number
listed in the RANK table excludes those documents that have been
flagged for deletion, whereas the number searched does not.
Refer to EMBASE's online guide in the BASE database for a full
description on Effective Thesaurus Searching - search as BASE-EMED.
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