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Reliable, unbiased, and evaluated information on drugs and medicines
used throughout the world.
Produced by the Royal Pharmaceutical Society of Great Britain,
Martindale has been the reference source of choice for practising
pharmacists and physicians since 1883 when the first edition was
published.
In addition to drugs and medicines, the database provides selected
investigational and veterinary drugs, herbal medicines,
pharmaceutical excipients, vitamins and nutritional agents,
vaccines, radiopharmaceuticals, contrast media and diagnostic
agents, medicinal gases, drugs of abuse and recreational drugs,
toxic substances, disinfectants, and pesticides are also included,
making Martindale an invaluable resource in all branches of
pharmaceutical science.
Martindale is regularly updated to ensure that it continues to meet
the information requirements of practitioners of medicine and
pharmacy. Information is derived from published sources and is
presented as sections of text with supporting referenced abstracts
and reviews.
The following information relating to drugs is covered: definitions
and descriptions, pharmacokinetics, adverse effects and treatments,
uses, precautions, administration, interactions, tradenames of
preparations.
Additionally, Martindale also contains disease treatment reviews
which provide overviews of diseases and the choice of treatments
available.
Details of commercial preparations from a wide range of countries
are searchable by tradename with cross-references to monographs for
their active ingredients where fuller information is given. A
directory of manufacturers of drug preparations worldwide, together
with their addresses, is included.
Use Martindale to answer questions like:
- what are the adverse effects associated with Fluticasone
Propionate?
- can antimuscarinic drugs be used in the treatment of gastro-
intestinal disorders?
- what is the molecular formula of Benzhexol Hydrochloride?
- in Thailand, a preparation called Abacus is available; what is it,
what are its properties, who manufactures it, and what is it used
to treat?
- are there any drugs which are useful in the treatment of hiccups?
- what are the constituent ingredients of the preparation Arelcant?
- what preparations are marketed by GlaxoSmithKline in Hong Kong?
Sources:
Sources covered by the database are: journals and periodicals,
licensed product literature, WHO publications, government reports
and legislation and other official and standard publications.
CHAPTER INTRODUCTION DOCUMENT
AN - Accession number & update
000000000330-a1-19-h 20010614.
TI - Title
Chapter title: Antimuscarinics;
Antimuscarinics: Introduction;
Anaesthesia.
TX - Text
Antimuscarinics, including atropine, hyoscine, and
glycopyrronium, have been used pre-operatively to inhibit
salivation and excessive secretions of the respiratory tract
during anaesthesia (3100-a4-45-v). This use is less
important now that less irritating anaesthetics are usedà
XR - Cross references
For the full drug monograph(s), see: 330-$.
AT - Document type
Introduction.
ED - Entry/revision date
Revision date: 19970311; 19980827; 19990628.
DRUG DEFINITION & DESCRIPTION DOCUMENT
AN - Accession number & update
000000000000000335-j 20010614.
TI - Title
Chapter title: Antimuscarinics;
Atropine Sulphate: Drug Definition and Description;
Atropine Sulphate (BANM).
SY - Synonyms
Synonyms: Atrop. Sulph. ; Atropine Sulfate; Atropini Sulfas
Read codes: y005m (Antiarrhythmic); y001K (Antispasmodic);
y00ln (Eyes); y03If (Premedication).
MO - Molecular formula/weight
(C17H23NO3)2, H2SO4, H -2O (694.8).
RN - CAS Registry number
55-48-1 (anhydrous atropine sulphate); 5908-99-6 (atropine
sulphate monohydrate).
PC - Pharmacopoeias
In Chin., Eur. (see 65000-a1-q), Int., Jpn, Pol., and US.
TX - Text
NOTE. Compounded preparations of atropine sulphate may be
represented by the following names:
Co-phenotrope (BAN) - atropine sulphate 1 part and
diphenoxylate hydrochloride 100 parts (w/w)à
DE - Descriptors
Co-phenotrope; ATR.
LK - Linked documents
For related derivatives, see: 331-w (Atropine); For
related derivatives, see: 332-e (Atropine Methobromide);
For related derivatives, see: 333-l (Atropine
Methonitrate).
XR - Cross references
For the full drug monograph(s), see: 335-$.
AT - Document type
Drug-Definition-and-Description.
ED - Entry/revision date
Revision date: 19970319; 19980828; 19990628.
PREPARATIONS DOCUMENT
AN - Accession number & update
000000065001-n6341-p 20010614.
TI - Title
Preparations: Actibil;
Actibil.
MF - Manufacturer
Arkopharma, France
IG - Ingredients
Cynara (3714-m); fumitory (8880-e).
IN - Indications
Gastrointestinal and urinary-tract disorders.
AT - Document type
Preparation.
ED - Entry/revision date
20031212.
Label/description Example
AN Accession number 1_: 330-A1-19-H.AN.
& update - see Limit options -
- all documents covering
a single substance 2_: 330-$.AN.
- see also Notes -
TI Title 3_: PORPHYRIA.TI.
- all docs from hard-copy
chapter on antimuscarinics 4_: CHAPTER WITH
ANTIMUSCARINICS.TI.
SY Synonyms 5_: Y005M.SY.
MF Manufacturer 6_: MERCK.MF.
MO Molecular formula 7_: H2SO4.MO.
RN CAS Registry number 8_: 55-48-1.RN.
PC Pharmacopoeias 9_: POL.PC.
TX Text 10_: GANGLION ADJ BLOCKING.TX.
IG Ingredients 11_: CYNARA.IG.
IN Indications 12_: URINARY ADJ TRACT.IN.
CR Cited references 13_: PIMSTONE.CR.
DE Descriptors 14_: CO-PHENOTROPE.DE.
LK Linked documents 15_: 331-W.LK.
or 16_: ATROPINE.LK.
XR Cross references 17_: 77-$.XR.
or 18_: ATROPINE.XR.
AT Document type
Drug definition & description 19_: AT=DRUG-DEFINITION-AND-
DESCRIPTION
Treatment reviews 20_: AT=TREATMENT-REVIEW
Preparations document 21_: AT=PREPARATION
Manufacturer name and address 22_: AT=MANUFACTURER
..ROOT AT= for a full list
ED Entry/revision date - see Limit options -
1_: ACTIBIL
ED Entry/revision date 2_: ..L 1 ED GT 20000726
UDATE Update date 3_: ..L UDATE EQ 20010713
UMONTH Update month 4_: ..L UMONTH WL
200107,200112
By paragraph - Title _: ..P TI 1-10
SHORT AN TI SY MO RN PC
MEDIUM AN TI SY MF MO RN PC TX IG IN CR LK XR
LONG AN TI SY MF MO RN PC TX IG IN CR DE LK XR
ALL AN TI SY MF MO RN PC TX IG IN CR DE LK XR AT ED
KWIC Context of search terms from the TX paragraph
FREE AN TI DE LK AT ED
_: ..P MED 1-3,5,7.
Retrieval of all documents relating to a single drug:
As in the old version, to retrieve all documents relating to a
single drug, you will need to use the accession number stem. In the
new MART, these accession numbers are now clearer and easier to use.
If you retrieve a document that is part of a drug-monograph and you
want to retrieve the rest of the information about the drug cited,
check the XR (Cited references) field where the accession number
stem is given, e.g.:
1 MART
AN 00000006117-a1-203-f 20010807.
TI Chapter title: Gastrointestinal Drugs;
Cimetidine: Adverse Effects;
Effects on the endocrine system.
TX Cimetidine has dose-related mild anti-androgenic
properties and reduced sperm counts and raised serum-
prolactin concentrations have been reported in men during
cimetidine treatment (1) as have gynaecomastia, breast
tenderness, and impotence...
CR 1. Wang C, et al. Effect of cimetidine on gonadal
function in man. Br J Clin Pharmacol 1982; 13: 791-4.
2. Jensen RT, et al. Cimetidine-induced impotence and
breast changes in patients with gastric hypersecretory
states. N Engl J Med 1983; 308: 883-7.
XR For the full drug monograph(s), see: 6117-$.
AT Adverse-Effects.
ED Revision date: 19960920; 19980304; 20000811.
Note that the accession number begins with the stem '6117-$'.
This can be searched in three ways:
_: 6117-$.AN.
This retrieves the 47 documents in the database which make up the
Cimetidine Drug Monograph in the hard-copy Martindale, or:
_: 6117-$.XR.
This retrieves the Cimetidine Drug Monograph documents, plus a
further 12 'treatment-review' documents in which Cimetidine is
referred to.
_: 6117-$
This retrieves 347 documents. It includes the drug monograph, the
treatment reveiws plus other documents in which Cimetidine is
mentioned - including those which cover the interaction of the drug
with other drugs, and 'preparation' type documents which include
Cimetidine as an ingredient.
For a complete guide to Martindale, search as BASE-MART in BASE.
MARTINDALE ONLINE:
This Database is the copyright of the Pharmaceutical Society of
Great Britain. Payment for information obtained through
MARTINDALE ONLINE includes the right to store the information in
memory and to print and display it for private use only. This
Database is provided "as is" without warranty of any kind,
either expressed or implied, including but not limited to, the
implied warranties of merchantability and fitness for a
particular purpose. The user is assumed to have the necessary
training to interpret the information the Database provides.
The Pharmaceutical Society of Great Britain cannot accept
responsibility for the uses to which the information is put.
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